Association between anemia and aflatoxin B1 biomarker levels among pregnant women in Kumasi, Ghana

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F.M.B. Shuaib; P.E. Jolly; J.E. Ehiri; Y. Jiang; W.O. Ellis; J.K. Stiles; N.J. Yatich; E. Funkhouser; S.D. Person; C. Wilson; J.H. Williams

Type of Document:
Scholarly Article


American Journal of Tropical Medicine and Hygiene

Date of Publication:

Place of Publication:
Not Available


Abstract. Aflatoxins are fungal metabolites that contaminate staple food crops in many developing countries. Up to 40% of women attending a prenatal clinic in Africa may be anemic. In a cross-sectional study of 755 pregnant women, Aflatoxin B 1 -lysine adducts (AF-ALB) levels were determined by high-performance liquid chromatography. Participants were divided into quartiles “low,” “moderate,” “high,” and “very high.” Anemia was defined as hemoglobin levels < 11 g/dL. Logistic regression was used to examine the association of anemia with AF-ALB. The mean AF-ALB level was 10.9 pg/mg (range = 0.44

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