Project
Improving Nutritional Status and CD4 Counts in HIV-Infected Children through Nutritional Support
Details
Project Code:
MSU-3
Start Date:
2010
End Date:
2012/12/31
CRSP Phase:
Phase 2
Budget:
$863,125
Countries:
Tanzania
Participants
Lead University:
Michigan State University
Other Partners:
SUA; CSU
Principal Investigator(s):
Maurice Bennink
Co-Principal Investigator(s):
None
Links
Overview
The overall goal of the research is to determine if eating beans or cowpeas will improve the immune status of children that are not being treated with antiretroviral drugs. The global theme addressed by this research is B ”To increase the utilization of bean and cowpea grain, food products and ingredients so as to expand market opportunities and improve community health and nutrition” and the topical area that will be addressed is 2 ”Achieving Nutritional Security for Improved Health of Target Populations”. HIV has caused an estimated 25 million deaths worldwide in just 27 years and there are approximately 33 million people in the world infected with HIV. Around 2 million children less than 15 years of age have HIV and 90% of the children living with
Objectives
1. Determine if HIV infected, HAARV naive, 2 to 15 year old children and adolescents eating a bean-maize or cowpea-maize supplement will maintain higher CD4 % than HIV infected, HAARV naive, 2 to 15 year old children and adolescents eating a fish-maize supplement. 2. Determine the relative costs of five dietary treatments compared to HAARV drug treatment (Note: this will complete the data gathering begun in FY10). 3. Determine if eating the bean-based supplement improves the integrity of the mucosal barrier in the gut and leads to reduced gut permeability and release of pro-inflammatory cytokines. 4. Capacity Building
Outcomes
Coming soon
